ZNF274 antibody (N-Term)

Catalog No. ABIN1882019

Product Details anti-ZNF274 Antibody

Target: ZNF274 (Zinc Finger Protein 274 (ZNF274))

Binding Specificity: AA 53-82, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF274 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZNF274 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the N-terminal region of human ZNF274.

Clone: RB40414

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ZNF274 antibody (ABIN1882019)

Wu, Ma, Brown, Geisler, Li, Tzeng, Jia, Jurisica, Li: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." in: Proteomics, Vol. 7, Issue 11, pp. 1775-85, (2007) (PubMed).

Sripathy, Stevens, Schultz: "The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression." in: Molecular and cellular biology, Vol. 26, Issue 22, pp. 8623-38, (2006) (PubMed).

Casademunt, Carter, Benzel, Frade, Dechant, Barde: "The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death." in: The EMBO journal, Vol. 18, Issue 21, pp. 6050-61, (2000) (PubMed).

Yano, Ueki, Oda, Seki, Masuho, Muramatsu: "Identification and characterization of human ZNF274 cDNA, which encodes a novel kruppel-type zinc-finger protein having nucleolar targeting ability." in: Genomics, Vol. 65, Issue 1, pp. 75-80, (2000) (PubMed).

Target Details for ZNF274

Target: ZNF274 (Zinc Finger Protein 274 (ZNF274))

Alternative Name: ZNF274 (ZNF274 Products)

Background: This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals.

Molecular Weight: 74177

NCBI Accession: NP_001265663, NP_001265664, NP_057408, NP_057409, NP_598009

UniProt: Q96GC6