ACTR2 antibody (AA 191-219)

Catalog No. ABIN1882060

This Rabbit Polyclonal antibody specifically detects ACTR2 in WB, FACS and IHC (p). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for ACTR2 antibody (AA 191-219) (ABIN1882060)

Target: ACTR2 (Actin-Related Protein 2 (ACTR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTR2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB19692

Product Details anti-ACTR2 Antibody

Binding Specificity: AA 191-219

Predicted Reactivity: X, B, C, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ACTR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of human ACTR2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-ACTR2 antibody (ABIN1882060)

Gonzalez, Combe, David, Malmquist, Delorme, Leroy, Blazquez, Ménard, Tardieux: "Host cell entry by apicomplexa parasites requires actin polymerization in the host cell." in: Cell host & microbe, Vol. 5, Issue 3, pp. 259-72, (2009) (PubMed).

Weisswange, Newsome, Schleich, Way: "The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motility." in: Nature, Vol. 458, Issue 7234, pp. 87-91, (2009) (PubMed).

Target Details for ACTR2

Target: ACTR2 (Actin-Related Protein 2 (ACTR2))

Alternative Name: ACTR2

Background: ACTR2 is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.

Molecular Weight: 44761

NCBI Accession: NP_001005386, NP_005713

UniProt: P61160

Pathways: RTK Signaling, Regulation of Actin Filament Polymerization