APOA2 antibody (AA 28-56)

Catalog No. ABIN1882063

This Rabbit Polyclonal antibody specifically detects APOA2 in WB and IHC (p). It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for APOA2 antibody (AA 28-56) (ABIN1882063)

Target: APOA2 (Apolipoprotein A-II (APOA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB15149

Product Details anti-APOA2 Antibody

Binding Specificity: AA 28-56

Predicted Reactivity: Pr

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This APOA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the Central region of human APOA2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-APOA2 antibody (ABIN1882063)

Duesing, Charpentier, Marre, Tichet, Hercberg, Balkau, Froguel, Gibson: "Evaluating the association of common APOA2 variants with type 2 diabetes." in: BMC medical genetics, Vol. 10, pp. 13, (2009) (PubMed).

Atta, Crook, Shafique, Johnston, Godsland: "Procoagulant activities of plasma factor VIIc and factor Xc are positively and independently associated with concentrations of the high-density lipoprotein apolipoprotein, apo A-II." in: Thrombosis and haemostasis, Vol. 100, Issue 3, pp. 391-6, (2008) (PubMed).

Target Details for APOA2

Target: APOA2 (Apolipoprotein A-II (APOA2))

Alternative Name: APOA2

Background: APOA2, apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.

Molecular Weight: 11175

NCBI Accession: NP_001634

UniProt: P02652

Pathways: Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Negative Regulation of Transporter Activity, Lipid Metabolism