JAM3 antibody (C-Term)

Catalog No. ABIN1882171

This Rabbit Polyclonal antibody specifically detects JAM3 in WB. It exhibits reactivity toward Human, Mouse, Rat and has been mentioned in 3+ publications.

Quick Overview for JAM3 antibody (C-Term) (ABIN1882171)

Target: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAM3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB47643

Product Details anti-JAM3 Antibody

Binding Specificity: AA 261-295, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This JAM3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 261-295 amino acids from the C-terminal region of human JAM3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-JAM3 antibody (ABIN1882171)

Santoso, Sachs, Kroll, Linder, Ruf, Preissner, Chavakis: "The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1." in: The Journal of experimental medicine, Vol. 196, Issue 5, pp. 679-91, (2002) (PubMed).

Phillips, Renforth, Spalluto, Hearn, Curtis, Craven, Havarani, Clement-Jones, English, Stumper, Salmon, Hutchinson, Jackson, Wilson: "Narrowing the critical region within 11q24-qter for hypoplastic left heart and identification of a candidate gene, JAM3, expressed during cardiogenesis." in: Genomics, Vol. 79, Issue 4, pp. 475-8, (2002) (PubMed).

Arrate, Rodriguez, Tran, Brock, Cunningham: "Cloning of human junctional adhesion molecule 3 (JAM3) and its identification as the JAM2 counter-receptor." in: The Journal of biological chemistry, Vol. 276, Issue 49, pp. 45826-32, (2001) (PubMed).

Target Details for JAM3

Target: JAM3 (Junctional Adhesion Molecule 3 (JAM3))

Alternative Name: JAM3

Background: Participates in cell-cell adhesion. It is a counter- receptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN). The soluble form is a mediator of angiogenesis.

Molecular Weight: 35020

UniProt: Q9BX67