Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.50-1.500
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
PITRM1
(Pitrilysin Metallopeptidase 1 (PITRM1))
Alternative Name
MP1
Background
This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade.The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2.Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation.Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein.[provided by RefSeq]