APRT antibody (AA 1-104)

Catalog No. ABIN1885569

The Rabbit Polyclonal anti-APRT antibody (ABIN1885569) specifically detects APRT in WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for APRT antibody (AA 1-104) (ABIN1885569)

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APRT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-APRT Antibody

Binding Specificity: AA 1-104

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 104 of APRT

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for APRT

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Alternative Name: APRT

Background: Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family.A conserved feature of this gene is the distribution of CpG dinucleotides.This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP).It also produces adenine as a by-product of the polyamine biosynthesis pathway.A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Molecular Weight: 15 kDa

Gene ID: 353

NCBI Accession: NP_001025189, NM_001030018

Pathways: Ribonucleoside Biosynthetic Process