NXF1 antibody (AA 1-121)

Catalog No. ABIN1885590

This anti-NXF1 antibody is a Rabbit Polyclonal antibody detecting NXF1 in WB, IHC and IF. Suitable for Human.

Quick Overview for NXF1 antibody (AA 1-121) (ABIN1885590)

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NXF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NXF1 Antibody

Binding Specificity: AA 1-121

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 121 of TAP

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1 x PBS, 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for NXF1

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Alternative Name: nuclear RNA export factor 1

Background: This gene is one member of a family of nuclear RNA export factor genes.Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins.The LRRs and NTF2-like domains are required for export activity.Alternative splicing seems to be a common mechanism in this gene family.The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA.It is the vertebrate homologue of the yeast protein Mex67p.The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.Alternative splicing results in multiple transcript variants.[provided by RefSeq]

Molecular Weight: 70 kDa

Gene ID: 10482

NCBI Accession: NP_006353, NM_006362