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NXF1 antibody (C-Term)

NXF1 Reactivity: Human WB, IP, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855276
  • Target See all NXF1 Antibodies
    NXF1 (Nuclear RNA Export Factor 1 (NXF1))
    Binding Specificity
    • 12
    • 12
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 55
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    Human
    Host
    • 55
    • 1
    Rabbit
    Clonality
    • 46
    • 10
    Polyclonal
    Conjugate
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NXF1 antibody is un-conjugated
    Application
    • 38
    • 22
    • 19
    • 8
    • 7
    • 5
    • 4
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Sequence
    CSSGALDYDI PTTASENLYF Q
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit Polyclonal antibody to TAP (nuclear RNA export factor 1)
    TAP antibody [C2C3], C-term
    Purification
    Affinity purified by Protein A.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human TAP. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product NXF1 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Mouse brain , A431

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    10.00 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    NXF1 (Nuclear RNA Export Factor 1 (NXF1))
    Alternative Name
    nuclear RNA export factor 1 (NXF1 Products)
    Synonyms
    im:7156527 antibody, wu:fc12d06 antibody, MGC82224 antibody, NXF1 antibody, tap antibody, mex67 antibody, MEX67 antibody, TAP antibody, Mex67 antibody, Mvb1 antibody, Tap antibody, Mex67h antibody, nuclear RNA export factor 1 antibody, nuclear RNA export factor 1 S homeolog antibody, Nuclear RNA export factor 1 antibody, nxf1 antibody, nxf1.S antibody, NXF1 antibody, LOC100113601 antibody, Tsp_03999 antibody, Nxf1 antibody, nxf-1 antibody
    Background
    This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants.

    Cellular Localization: Nucleus , nucleoplasm , Nucleus speckle , Cytoplasm
    Molecular Weight
    70 kDa
    Gene ID
    10482
    UniProt
    Q9UBU9
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