DUSP8 antibody (AA 1-14)

Catalog No. ABIN1885611

The Rabbit Polyclonal anti-DUSP8 antibody (ABIN1885611) specifically detects DUSP8 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for DUSP8 antibody (AA 1-14) (ABIN1885611)

Target: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP8 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-DUSP8 Antibody

Binding Specificity: AA 1-14

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 14 of Human DUSP8

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for DUSP8

Target: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Alternative Name: DUSP8

Background: The protein encoded by this gene is a member of the dualprotein phosphatase subfamily.These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation.Different members of the family of dualphosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.[provided by RefSeq]

Molecular Weight: 66 kDa

Gene ID: 1850

NCBI Accession: NP_004411, NM_004420