CHMP5 antibody (AA 1-172)

Catalog No. ABIN1885686

The Rabbit Polyclonal anti-CHMP5 antibody (ABIN1885686) specifically detects CHMP5 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for CHMP5 antibody (AA 1-172) (ABIN1885686)

Target: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CHMP5 Antibody

Binding Specificity: AA 1-172

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 172 of Human CHMP5

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for CHMP5

Target: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Alternative Name: CHMP5

Background: CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family.These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs).Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM]

Molecular Weight: 25 kDa

Gene ID: 51510

NCBI Accession: NM_016410, NP_057494