Endothelin 3 antibody (AA 1-187)

Catalog No. ABIN1885737

This anti-Endothelin 3 antibody is a Rabbit Polyclonal antibody detecting Endothelin 3 in WB. Suitable for Human.

Quick Overview for Endothelin 3 antibody (AA 1-187) (ABIN1885737)

Target: Endothelin 3 (EDN3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endothelin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Endothelin 3 Antibody

Binding Specificity: AA 1-187

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 187 of Human EDN3

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Endothelin 3

Target: Endothelin 3 (EDN3)

Alternative Name: ET-3

Background: The protein encoded by this gene is a member of the endothelin family.Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions.The active form of this protein is a 21 amino acid peptide processed from the precursor protein.The active peptide is a ligand for endothelin receptor type B (EDNRB).The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons.Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells.Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.[provided by RefSeq]

Molecular Weight: 25 kDa

Gene ID: 1908

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones