MTAP antibody (AA 1-253)

Catalog No. ABIN1885849

This Rabbit Polyclonal antibody specifically detects MTAP in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for MTAP antibody (AA 1-253) (ABIN1885849)

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MTAP Antibody

Binding Specificity: AA 1-253

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 253 of Human MTAP

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for MTAP

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Alternative Name: MTAP

Background: This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine.The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted.Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.[provided by RefSeq]

Molecular Weight: 31 kDa

Gene ID: 4507

NCBI Accession: NM_002451, NP_002442

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process