MRPL41 antibody (AA 1-302)

Catalog No. ABIN1885895

The Rabbit Polyclonal anti-MRPL41 antibody has been validated for WB, IHC and IF. It is suitable to detect MRPL41 in samples from Human.

Quick Overview for MRPL41 antibody (AA 1-302) (ABIN1885895)

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL41 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPL41 Antibody

Binding Specificity: AA 1-302

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 302 of PIG3

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for MRPL41

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Alternative Name: PIG3

Background: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation.This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death.It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence.P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence.The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53.It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer.At least two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq]

Molecular Weight: 36 kDa

Gene ID: 9540

NCBI Accession: NM_004881, NP_004872

Pathways: p53 Signaling