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UNC13D antibody (AA 1029-1090)

The Rabbit Polyclonal anti-UNC13D antibody has been validated for WB, IHC and IF. It is suitable to detect UNC13D in samples from Human.
Catalog No. ABIN1885943

Quick Overview for UNC13D antibody (AA 1029-1090) (ABIN1885943)

Target

See all UNC13D Antibodies
UNC13D (Unc-13 Homolog D (UNC13D))

Reactivity

  • 24
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 20
  • 3
  • 2
Rabbit

Clonality

  • 23
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Polyclonal

Conjugate

  • 21
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  • 1
  • 1
This UNC13D antibody is un-conjugated

Application

  • 20
  • 11
  • 7
  • 3
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  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Binding Specificity

    • 5
    • 5
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    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1029-1090

    Purification

    Purified by antigen-affinity chromatography.

    Immunogen

    Synthetic peptide contain a sequence corresponding to a region within amino acids 1029 and 1090 of Human UNC13D
  • Application Notes

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.250
    Immunofluorescence: 1.100-1.200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    Preservative

    Thimerosal (Merthiolate)

    Precaution of Use

    Biohazard Informations: This product contains thimerosal which is hazardous.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target

    UNC13D (Unc-13 Homolog D (UNC13D))

    Alternative Name

    UNC13D

    Background

    This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins.The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion.Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.[provided by RefSeq]

    Molecular Weight

    123 kDa

    Gene ID

    201294

    NCBI Accession

    NP_954712, NM_199242

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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