DEDD
Reactivity: Human, Rat
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 750
Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
DEDD
(Death Effector Domain Containing (DEDD))
Alternative Name
DEDD
Background
This gene encodes a protein that contains a death effector domain (DED).DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway.Overexpression of this gene was shown to induce weak apoptosis.Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus.At least three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq]