DEDD antibody (AA 90-170)

Catalog No. ABIN7228178

The Rabbit Polyclonal anti-DEDD antibody (ABIN7228178) specifically detects DEDD in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for DEDD antibody (AA 90-170) (ABIN7228178)

Target: DEDD (Death Effector Domain Containing (DEDD))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEDD antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DEDD Antibody

Binding Specificity: AA 90-170

Purpose: Rabbit Anti-DEDD Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DEDD protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DEDD protein at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DEDD

Target: DEDD (Death Effector Domain Containing (DEDD))

Alternative Name: DEDD

Background: Death effector domain-containing protein, DEDPro1, Death effector domain-containing testicular molecule, FLDED-1DEDD encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 34kD

Gene ID: 9191

UniProt: O75618