FIG4 antibody (AA 135-400)

Catalog No. ABIN1886021

The Rabbit Polyclonal anti-FIG4 antibody has been validated for WB and IHC. It is suitable to detect FIG4 in samples from Human.

Quick Overview for FIG4 antibody (AA 135-400) (ABIN1886021)

Target: FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FIG4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FIG4 Antibody

Binding Specificity: AA 135-400

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 135 and 400 of FIG4

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for FIG4

Target: FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))

Alternative Name: FIG4

Background: The protein encoded by this gene belongs to the SAC domain-containing protein gene family.The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity.The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology.Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells.Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.[provided by RefSeq]

Molecular Weight: 104 kDa

Gene ID: 9896

NCBI Accession: NP_055660, NM_014845

Pathways: Inositol Metabolic Process