PROC antibody (AA 145-453)

Catalog No. ABIN1886047

This Rabbit Polyclonal antibody specifically detects PROC in WB. It exhibits reactivity toward Human.

Quick Overview for PROC antibody (AA 145-453) (ABIN1886047)

Target: PROC (Vitamin K-dependent protein C (PROC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PROC Antibody

Binding Specificity: AA 145-453

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 145 and 453 of Human PROC

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for PROC

Target: PROC (Vitamin K-dependent protein C (PROC))

Alternative Name: Protein C

Background: The PROC gene encodes protein C (EC 3.4.21.69), a vitamin K-dependent plasma glycoprotein that is a key component of the anticoagulant system.Protein C is cleaved to its activated form, 'activated protein C' (APC) on endothelial cells by the thrombin-thrombomodulin complex (MIM 176930, MIM 188040) and then acts as a serine protease to degrade the activated forms of coagulation factors V (F5, MIM 612309) and VIII (F8, see MIM 306700).Protein S (PROS1, MIM 176880), also a vitamin K-dependent plasma protein, functions as a cofactor to activated protein C.[supplied by OMIM]

Molecular Weight: 52 kDa

Gene ID: 5624

NCBI Accession: NM_000312, NP_000303