FPGT antibody (AA 146-423)

Catalog No. ABIN1886052

The Rabbit Polyclonal anti-FPGT antibody (ABIN1886052) specifically detects FPGT in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for FPGT antibody (AA 146-423) (ABIN1886052)

Target: FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPGT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FPGT Antibody

Binding Specificity: AA 146-423

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 146 and 423 of Human FPGT

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for FPGT

Target: FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))

Alternative Name: FPGT

Background: L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition.The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose.There are two alternate pathways for the biosynthesis of GDP-fucose, the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose.The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids.This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose.[provided by RefSeq]
Synonyms: GFPP

Molecular Weight: 67 kDa

Gene ID: 8790

NCBI Accession: NP_003829, NM_003838