CLDN14 antibody (AA 177-189)

Catalog No. ABIN1886114

The Rabbit Polyclonal anti-CLDN14 antibody is suitable to detect CLDN14 in samples from Human. It has been validated for WB.

Quick Overview for CLDN14 antibody (AA 177-189) (ABIN1886114)

Target: CLDN14 (Claudin 14 (CLDN14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLDN14 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLDN14 Antibody

Binding Specificity: AA 177-189

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 177 and 189 (O95500) of Claudin 14

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1 x PBS, 40 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for CLDN14

Target: CLDN14 (Claudin 14 (CLDN14))

Alternative Name: claudin 14

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet.The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands.The encoded protein also binds specifically to the WW domain of Yes-associated protein.Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness.Several transcript variants encoding the same protein have been found for this gene.[provided by RefSeq]

Molecular Weight: 26 kDa

Gene ID: 23562

NCBI Accession: NM_012130, NP_036262

Pathways: Cell-Cell Junction Organization, Hepatitis C