Progesterone Receptor antibody (AA 18-82)

Catalog No. ABIN1886122

This Rabbit Polyclonal antibody specifically detects Progesterone Receptor in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for Progesterone Receptor antibody (AA 18-82) (ABIN1886122)

Target: Progesterone Receptor (PGR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Progesterone Receptor Antibody

Binding Specificity: AA 18-82

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 18 and 82 of Progesterone receptor

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: Progesterone receptor

Background: This gene encodes a member of the steroid receptor superfamily.The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B.The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.The location of transcription initiation for isoform A has not been clearly determined.[provided by RefSeq]

Molecular Weight: 99 kDa

Gene ID: 5241

NCBI Accession: NM_000926, NP_000917

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration