MAPKAPK5
Reactivity: Human
WB, PLA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
MAPKAP Kinase 5 (MAPKAPK5)
(Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
Alternative Name
PRAK
Background
The protein encoded by this gene is a member of the serine/threonine kinase family.In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta.In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites.Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.[provided by RefSeq]