Cytokeratin 13 antibody (AA 198-448)

Catalog No. ABIN1886161

This Rabbit Polyclonal antibody specifically detects Cytokeratin 13 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for Cytokeratin 13 antibody (AA 198-448) (ABIN1886161)

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytokeratin 13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Cytokeratin 13 Antibody

Binding Specificity: AA 198-448

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 198 and 448 of Cytokeratin 13

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Cytokeratin 13

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Alternative Name: Cytokeratin 13

Background: The protein encoded by this gene is a member of the keratin gene family.The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins.Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains.This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia.Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.The type I cytokeratins are clustered in a region of chromosome 17q21.2.Alternative splicing of this gene results in multiple transcript variants, however, not all variants have been described.[provided by RefSeq]

Molecular Weight: 50 kDa

Gene ID: 3860

NCBI Accession: NM_153490, NP_705694