GALNS antibody (AA 20-269)

Catalog No. ABIN1886170

This Rabbit Polyclonal antibody specifically detects GALNS in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for GALNS antibody (AA 20-269) (ABIN1886170)

Target: GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALNS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GALNS Antibody

Binding Specificity: AA 20-269

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 20 and 269 of GALNS

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for GALNS

Target: GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))

Alternative Name: GALNS

Background: This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate.Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme.Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.[provided by RefSeq]

Molecular Weight: 58 kDa

Gene ID: 2588

NCBI Accession: NP_000503, NM_000512

Pathways: Glycosaminoglycan Metabolic Process