AKR1C1 antibody (AA 22-218)

Catalog No. ABIN1886214

This anti-AKR1C1 antibody is a Rabbit Polyclonal antibody detecting AKR1C1 in WB, IHC and IF. Suitable for Human.

Quick Overview for AKR1C1 antibody (AA 22-218) (ABIN1886214)

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR1C1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-AKR1C1 Antibody

Binding Specificity: AA 22-218

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 22 and 218 of Human AKR1C1

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for AKR1C1

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Alternative Name: AKR1C1

Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins.These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors.The enzymes display overlapping but distinct substrate.This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.[provided by RefSeq]

Molecular Weight: 37 kDa

Gene ID: 1645

NCBI Accession: NP_001344, NM_001353

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process