Complement C2 antibody (AA 265-612)

Catalog No. ABIN1886288

The Rabbit Polyclonal anti-Complement C2 antibody has been validated for WB and IF. It is suitable to detect Complement C2 in samples from Human.

Quick Overview for Complement C2 antibody (AA 265-612) (ABIN1886288)

Target: Complement C2

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Complement C2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Complement C2 Antibody

Binding Specificity: AA 265-612

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 265 and 612 of Human C2

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Complement C2

Target: Complement C2

Background: Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system.Activated C1 cleaves C2 into C2a and C2b.The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase.Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration.This gene localizes within the class III region of the MHC on the short arm of chromosome 6.Alternative splicing results in multiple transcript variants encoding distinct isoforms.Additional transcript variants have been described in publications but their full-length sequence has not been determined.

Molecular Weight: 83 kDa

Gene ID: 717

NCBI Accession: NP_000054, NM_000063