Coagulation Factor X antibody (AA 33-282)

Catalog No. ABIN1886374

This Rabbit Polyclonal antibody specifically detects Coagulation Factor X in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for Coagulation Factor X antibody (AA 33-282) (ABIN1886374)

Target: Coagulation Factor X (F10)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Coagulation Factor X antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Coagulation Factor X Antibody

Binding Specificity: AA 33-282

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 33 and 282 of Human F10

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Coagulation Factor X

Target: Coagulation Factor X (F10)

Alternative Name: Factor X

Background: This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade.This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR.Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases.The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway).The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.[provided by RefSeq]

Molecular Weight: 55 kDa

Gene ID: 2159

NCBI Accession: NM_000504, NP_000495