FASTK antibody (AA 346-521)
Quick Overview for FASTK antibody (AA 346-521) (ABIN1886387)
Target
See all FASTK AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 346-521
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Purification
- Affinity purified by Protein A.
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Immunogen
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 346 and 521 of FAST
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Application Notes
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- FASTK (Fas-Activated serine/threonine Kinase (FASTK))
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Alternative Name
- FAST
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Background
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The protein encoded by this gene is a member of the serine/threonine protein kinase family.This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells.In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein.The encoded protein is a strong inducer of lymphocyte apoptosis.Two transcript variants encoding different isoforms have been found for this gene.Other variants exist, but their full-length natures have not yet been determined.[provided by RefSeq]
Synonyms: FAST -
Molecular Weight
- 61 kDa
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Gene ID
- 10922
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NCBI Accession
- NP_006703, NM_006712
Target
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