INHBA antibody (AA 362-423)

Catalog No. ABIN1886407

This Rabbit Polyclonal antibody specifically detects INHBA in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for INHBA antibody (AA 362-423) (ABIN1886407)

Target: INHBA (Inhibin, beta A (INHBA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INHBA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-INHBA Antibody

Binding Specificity: AA 362-423

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 362 and 423 of Inhibin beta-A

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for INHBA

Target: INHBA (Inhibin, beta A (INHBA))

Alternative Name: Inhibin beta-A

Background: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor.Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity.In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease.Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.[provided by RefSeq]

Molecular Weight: 47 kDa

Gene ID: 3624

NCBI Accession: NM_002192, NP_002183

Pathways: Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy