Prohibitin 2 antibody (AA 45-298)

Catalog No. ABIN1886480

The Rabbit Polyclonal anti-Prohibitin 2 antibody has been validated for WB, IHC and IF. It is suitable to detect Prohibitin 2 in samples from Human.

Quick Overview for Prohibitin 2 antibody (AA 45-298) (ABIN1886480)

Target: Prohibitin 2 (PHB2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prohibitin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Prohibitin 2 Antibody

Binding Specificity: AA 45-298

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 45 and 298 of REA

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Prohibitin 2

Target: Prohibitin 2 (PHB2)

Alternative Name: REA

Background: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity).Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens.Competes with NCOA1 for modulation of ER transcriptional activity.Probably involved in regulating mitochondrial respiration activity and in aging.

Molecular Weight: 33 kDa

Gene ID: 11331

NCBI Accession: NM_007273, NP_009204

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling