LOXL2 antibody (AA 454-712)

Catalog No. ABIN1886482

This Rabbit Polyclonal antibody specifically detects LOXL2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for LOXL2 antibody (AA 454-712) (ABIN1886482)

Target: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOXL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LOXL2 Antibody

Binding Specificity: AA 454-712

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 454 and 712 of human LOXL2

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for LOXL2

Target: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Alternative Name: LOXL2

Background: This gene encodes a member of the lysyl oxidase gene family.The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin.A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function.The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.[provided by RefSeq]

Molecular Weight: 87 kDa

Gene ID: 4017

NCBI Accession: NM_002318, NP_002309

Pathways: Chromatin Binding