PFKL antibody (AA 475-691)

Catalog No. ABIN1886499

This anti-PFKL antibody is a Rabbit Polyclonal antibody detecting PFKL in WB, IHC and IF. Suitable for Human.

Quick Overview for PFKL antibody (AA 475-691) (ABIN1886499)

Target: PFKL (Phosphofructokinase, Liver (PFKL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFKL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PFKL Antibody

Binding Specificity: AA 475-691

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 475 and 691 of PFKL

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for PFKL

Target: PFKL (Phosphofructokinase, Liver (PFKL))

Alternative Name: PFKL

Background: Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate.Separate genes encode a muscle subunit (M) and a liver subunit (L).PFK from muscle is a homotetramer of M subunits, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits.The protein encoded by this gene represents the L subunit.Alternate splicing results in two transcript variants, one of which is a candidate for nonsense-mediated decay (NMD).[provided by RefSeq]

Molecular Weight: 90 kDa

Gene ID: 5211

NCBI Accession: NP_001002021, NM_001002021

Pathways: Negative Regulation of Hormone Secretion, Warburg Effect