Complement Factor H antibody (AA 527-588)
Quick Overview for Complement Factor H antibody (AA 527-588) (ABIN1886532)
Target
See all Complement Factor H (CFH) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 527-588
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Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- 527 - 588 of Human Complement factor H
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Application Notes
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Suggested dilutions:
Western blotting: 1.500-1.3000 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Complement Factor H (CFH)
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Alternative Name
- Complement factor H
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Background
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This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains.This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections.Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy.Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[provided by RefSeq]
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Molecular Weight
- 139 kDa
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Gene ID
- 3075
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NCBI Accession
- NP_000177, NM_000186
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Pathways
- Complement System, Cellular Response to Molecule of Bacterial Origin
Target
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