SART1 antibody (AA 533-762)

Catalog No. ABIN1886540

The Rabbit Polyclonal anti-SART1 antibody is suitable to detect SART1 in samples from Human. It has been validated for WB.

Quick Overview for SART1 antibody (AA 533-762) (ABIN1886540)

Target: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SART1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SART1 Antibody

Binding Specificity: AA 533-762

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 533 and 762 of human SART1

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for SART1

Target: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Alternative Name: SART1

Background: This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers.The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet.The two encoded proteins are thought to be involved in the regulation of proliferation.Both proteins have tumor-rejection antigens.The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients.This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy.The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.[provided by RefSeq]

Molecular Weight: 90 kDa

Gene ID: 9092

NCBI Accession: NM_005146, NP_005137

Pathways: Ribonucleoprotein Complex Subunit Organization