NANS antibody (AA 54-341)

Catalog No. ABIN1886546

The Rabbit Polyclonal anti-NANS antibody is suitable to detect NANS in samples from Human. It has been validated for WB and IHC.

Quick Overview for NANS antibody (AA 54-341) (ABIN1886546)

Target: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NANS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NANS Antibody

Binding Specificity: AA 54-341

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 54 and 341 of NANS

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for NANS

Target: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Alternative Name: NANS

Background: This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids.In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product.In insect cells, expression of this gene results in Neu5Ac and KDN production.This gene is related to the E.coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E.coli neuB-negative mutant.[provided by RefSeq]
Synonyms: SAS

Molecular Weight: 40 kDa

Gene ID: 54187

NCBI Accession: NP_061819, NM_018946