Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.250
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
AKAP10
(A Kinase (PRKA) Anchor Protein 10 (AKAP10))
Alternative Name
AKAP10
Background
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell.This gene encodes a member of the AKAP family.The encoded protein interacts with both the type I and type II regulatory subunits of PKA, therefore, it is a dual-specific AKAP.This protein is highly enriched in mitochondria.It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain.The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.[provided by RefSeq]