beta Amyloid antibody (AA 602-757)

Catalog No. ABIN1886574

The Rabbit Polyclonal anti-beta Amyloid antibody (ABIN1886574) specifically detects beta Amyloid in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for beta Amyloid antibody (AA 602-757) (ABIN1886574)

Target: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta Amyloid antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-beta Amyloid Antibody

Binding Specificity: AA 602-757

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 602 and 757 of Human APP

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for beta Amyloid

Target: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Alternative Name: beta-Amyloid

Background: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides.Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease.Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).Multiple transcript variants encoding several different isoforms have been found for this gene.[provided by RefSeq]

Molecular Weight: 87 kDa

Gene ID: 351

NCBI Accession: NM_000484, NP_000475

Pathways: Inflammasome