CKMT1B antibody (AA 63-297)

Catalog No. ABIN1886588

The Rabbit Polyclonal anti-CKMT1B antibody is suitable to detect CKMT1B in samples from Human. It has been validated for WB and IHC.

Quick Overview for CKMT1B antibody (AA 63-297) (ABIN1886588)

Target: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CKMT1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CKMT1B Antibody

Binding Specificity: AA 63-297

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 63 and 297 of Human CKMT1B

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for CKMT1B

Target: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Alternative Name: Creatine kinase(mitochondrial 1B)

Background: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine.It belongs to the creatine kinase isoenzyme family.It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes.Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes.Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis.Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.[provided by RefSeq]
Synonyms: CKMT, CKMT1, UMTCK

Molecular Weight: 47 kDa

Gene ID: 1159

NCBI Accession: NP_066270, NM_020990