Suggested dilutions: Western blotting: 1.500-1.3000
Restrictions
For Research Use only
Format
Liquid
Buffer
1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
EML1
(Echinoderm Microtubule Associated Protein Like 1 (EML1))
Alternative Name
EML1
Background
Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene.Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type.The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems.The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3).The type I is the most severe form.Gene loci responsible for these three types are all mapped.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]