EML1 antibody (C-Term)

Catalog No. ABIN2784635

The Rabbit Polyclonal anti-EML1 antibody is suitable to detect EML1 in samples from Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for EML1 antibody (C-Term) (ABIN2784635)

Target: EML1 (Echinoderm Microtubule Associated Protein Like 1 (EML1))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EML1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EML1 Antibody

Binding Specificity: C-Term

Purpose: EML1 Antibody - C-terminal region

Sequence: YPCSQFRAPS HIYGGHSSHV TNVDFLCEDS HLISTGGKDT SIMQWRVI

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against EML1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EML1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51803-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for EML1

Target: EML1 (Echinoderm Microtubule Associated Protein Like 1 (EML1))

Alternative Name: EML1

Background:

Background Information: Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Echinoderm microtubule associated protein like 1

Alternative Symbols: BH, EMAP, ELP79, EMAPL, EMAP-1

Protein Name: Echinoderm microtubule-associated protein-like 1

Molecular Weight: 92kDa

Gene ID: 2009

NCBI Accession: NP_001008707

UniProt: O00423