UGT1A6 antibody (AA 8-187)

Catalog No. ABIN1886667

The Rabbit Polyclonal anti-UGT1A6 antibody (ABIN1886667) specifically detects UGT1A6 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for UGT1A6 antibody (AA 8-187) (ABIN1886667)

Target: UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGT1A6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-UGT1A6 Antibody

Binding Specificity: AA 8-187

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 8 and 187 (P19224) of UGT1A6

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for UGT1A6

Target: UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

Alternative Name: UGT1A6

Background: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites.This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases.The locus includes thirteen unique alternate first exons followed by four common exons.Four of the alternate first exons are considered pseudogenes.Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini.Each first exon encodes the substrate binding site, and is regulated by its own promoter.The enzyme encoded by this gene is active on phenolic and planar compounds.Alternative splicing in the unique 5' end of this gene results in two transcript variants.[provided by RefSeq]

Molecular Weight: 61 kDa

Gene ID: 54578

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha