RAMP1 antibody (AA 84-98)

Catalog No. ABIN1886682

This anti-RAMP1 antibody is a Rabbit Polyclonal antibody detecting RAMP1 in WB. Suitable for Human.

Quick Overview for RAMP1 antibody (AA 84-98) (ABIN1886682)

Target: RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAMP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAMP1 Antibody

Binding Specificity: AA 84-98

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 84 and 98 (O60894) of RAMP1

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for RAMP1

Target: RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))

Alternative Name: RAMP1

Background: The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs).RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus.RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane.CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed.In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor.The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.[provided by RefSeq]

Molecular Weight: 17 kDa

Gene ID: 10267

NCBI Accession: NM_005855, NP_005846

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process