RAMP1 antibody (Receptor (G Protein-Coupled) Activity Modifying Protein 1) (C-Term)

Details for Product anti-RAMP1 Antibody No. ABIN2856616
Antigen
  • RAMP1
  • MGC147096
  • 9130218E19Rik
  • receptor activity modifying protein 1
  • receptor (G protein-coupled) activity modifying protein 1
  • receptor (calcitonin) activity modifying protein 1
  • RAMP1
  • ramp1
  • Ramp1
Epitope
C-Term
15
10
4
4
2
2
1
1
1
Reactivity
Human
65
34
32
Host
Rabbit
58
7
5
2
Clonality
Polyclonal
Conjugate
This RAMP1 antibody is un-conjugated
4
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
45
24
13
5
3
2
Options
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RAMP1. The exact sequence is proprietary.
Isotype IgG
Cross-Reactivity Mouse (Murine), Rat (Rattus), Xenopus tropicalis, Pig (Porcine), Guinea Pig
Cross-Reactivity (Details) Mouse (93 %), Rat (93 %), Xenopus Tropicalis (87 %), Pig (86 %), Guinea pig (80 %)
Characteristics Rabbit polyclonal antibody to RAMP1 (receptor (G protein-coupled) activity modifying protein 1)
RAMP1 antibody [C1C3]
Purification Purified by antigen-affinity chromatography.
Plasmids, Primers & others Plasmids, Primers & others RAMP1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name RAMP1 (RAMP1 Antibody Abstract)
Background The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.

Cellular Localization: Membrane, Single-pass type I membrane protein
Molecular Weight 17 kDa
Gene ID 10267
Pathways cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
Application Notes Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
Comment

Positive Control: HepG2

Restrictions For Research Use only
Format Liquid
Concentration 0.87 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1) (C-Term) antibody (ABIN2856616) WB Image Sample (30 ug of whole cell lysate) A: Hep G2 , 12% SDS PAGE antibody dilute...
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