Arc antibody (AA 191-208)

Catalog No. ABIN1886845

This Rabbit Polyclonal antibody specifically detects Arc in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Arc antibody (AA 191-208) (ABIN1886845)

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Arc antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Arc Antibody

Binding Specificity: AA 191-208

Purification: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids 191 to 208 of human origin.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for Arc

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Alternative Name: ARC

Background: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases.CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2.A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD.ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8.ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3.The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.
Synonyms: ARC

Molecular Weight: 25 kDa

NCBI Accession: NP_003937