DRAK2 antibody (AA 351-365)

Catalog No. ABIN1886873

The Rabbit Polyclonal anti-DRAK2 antibody is suitable to detect DRAK2 in samples from Human. It has been validated for WB, ELISA and ICC.

Quick Overview for DRAK2 antibody (AA 351-365) (ABIN1886873)

Target: DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRAK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Product Details anti-DRAK2 Antibody

Binding Specificity: AA 351-365

Cross-Reactivity (Details): It has no cross responses to DAP or ZIP kinases. The approximately 70 kDa band is probably non-related to DRAK2 although it is peptide blockable.

Purification: Ion exchange chromatography purified

Immunogen: Peptide corresponding to amino acids 351 to 365 of human DRAK2.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for DRAK2

Target: DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

Alternative Name: DRAK2

Background: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases.Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis.Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases).DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain.Overexpression of DRAK2 induces apoptosis.DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities.DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.