IL21 Receptor antibody (AA 97-111)

Catalog No. ABIN1886904

This anti-IL21 Receptor antibody is a Rabbit Polyclonal antibody detecting IL21 Receptor in WB, ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for IL21 Receptor antibody (AA 97-111) (ABIN1886904)

Target: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL21 Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-IL21 Receptor Antibody

Binding Specificity: AA 97-111

Purification: Affinity chromatography purified via peptide column

Immunogen: Synthetic peptide corresponding to amino acids 97 to 111 of human IL-21 receptor precursor.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for IL21 Receptor

Target: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Alternative Name: IL-21 Receptor

Background: A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21.The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family.IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling.Both IL-21R and the gammac are necessary for the IL-21 function.IL-21 and its receptor activate JAK-STAT signaling pathway.IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines.IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
Synonyms: IL21R

Molecular Weight: 60 kDa

NCBI Accession: NP_068570

Pathways: JAK-STAT Signaling