DCAF12 antibody (C-Term)

Catalog No. ABIN1887065

The Rabbit Polyclonal anti-DCAF12 antibody is suitable to detect DCAF12 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and ICC.

Quick Overview for DCAF12 antibody (C-Term) (ABIN1887065)

Target: DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCAF12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Product Details anti-DCAF12 Antibody

Binding Specificity: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of human TCC52.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for DCAF12

Target: DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))

Alternative Name: TCC52

Background: Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types.Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors.One such CT antigen is TCC52, a novel centrosomal protein.TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates.The normal biological function of this protein is not known at this time.
Synonyms: Testis cancer centrosome-related protein 52, DDB1 and CUL4 associated factor 12, DCAF12, CT102, WDR40A

NCBI Accession: NP_056212