TMPRSS11A antibody (C-Term)

Catalog No. ABIN1887134

Product Details anti-TMPRSS11A Antibody

Target: TMPRSS11A (Transmembrane Protease, Serine 11A (TMPRSS11A))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS11A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): At least two isoforms of ECRG1 are known to exist, ECRG1 antibody is predicted to not cross-react with other ECRG family members.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human ECRG1.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for TMPRSS11A

Target: TMPRSS11A (Transmembrane Protease, Serine 11A (TMPRSS11A))

Alternative Name: ECRG1 (TMPRSS11A Products)

Synonyms: ECRG1 antibody, Gm7 antibody, transmembrane protease, serine 11A antibody, transmembrane protease serine 11A antibody, transmembrane protease, serine 11a antibody, TMPRSS11A antibody, LOC517049 antibody, LOC100482139 antibody, LOC100525933 antibody, Tmprss11a antibody

Background: Epidermal type-II transmembrane serine protease (ECRG1), also known as TMPRSS11A, is a member of a novel esophageal cancer-related gene family.It is a type-II transmembrane serine protease which may play a role in cellular senescence.It is expressed in esophagus, liver, colon and lung.Overexpression of ECRG1 inhibits cell growth and induces G1 cell cycle arrest.It is down-regulated in esophagus cancers (EC) and might play important roles in the initiation and progression of EC.
Synonyms: Esophageal cancer-susceptibility gene 1 protein, Airway trypsin-like protease 1, HATL1, HESP, TMPRSS11A

UniProt: Q6ZMR5