CEP164 antibody (N-Term)

Catalog No. ABIN1888154

Product Details anti-CEP164 Antibody

Target: CEP164 (Centrosomal Protein 164kDa (CEP164))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP164 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: CEP164 antibody was raised against an 18 amino acid peptide near the amino terminus of human CEP164.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for CEP164

Target: CEP164 (Centrosomal Protein 164kDa (CEP164))

Alternative Name: CEP164 (CEP164 Products)

Synonyms: AI450905 antibody, BC027092 antibody, D030051D21 antibody, mKIAA1052 antibody, RGD1560988 antibody, RGD1561243 antibody, NPHP15 antibody, centrosomal protein 164 antibody, CEP164 antibody, Cep164 antibody

Background: CEP164 was initially identified as a centrosomal protein, but other studies have indicated that it also plays a role in the formation of primary cilia, the microtubule-based sensory antennae projecting from the surface of many eukaryotic cells as well as in DNA damage response acting as a mediator protein.CEP164 interacts with both ATR and ATM, proteins that trigger a number of cellular responses including the initiation of DNA damaged-induced cell cycle checkpoints.It is phosphorylated upon replication stress, ultraviolet (UV) radiation, and ionizing radiation, silencing of CEP164 significantly reduces the DNA damage-induced phosphorylation of several proteins in the DNA damage-activated signaling cascade and compromises cell survival after UV damage.At least two isoforms of CEP164 are known to exist.
Synonyms: Centrosomal protein 164

NCBI Accession: NP_055771

Pathways: M Phase