Influenza Nucleoprotein antibody (Influenza A Virus H1N1)

Catalog No. ABIN1888259

The Rabbit Polyclonal anti- antibody has been validated for ELISA. It is suitable to detect in samples from Influenza A Virus H1N1.

Quick Overview for Influenza Nucleoprotein antibody (Influenza A Virus H1N1) (ABIN1888259)

Target: Influenza Nucleoprotein (NP)

Reactivity: Influenza A Virus H1N1

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA

Product Details

Specificity: This antibody is specific for the seasonal H1N1 influenza NP and will not recognize the corresponding NP sequence from the swine-origin H1N1 influenza (A/California/14/2009 (H1N1)).

Purification: Affinity chromatography purified via peptide column

Immunogen: synthetic peptide from the seasonal H1N1 NP protein.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details

Target: Influenza Nucleoprotein (NP)

Alternative Name: Influenza Nucleoprotein

Target Type: Influenza Protein

Background: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA.In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States.The influenza A virus polymerase transcribes and replicates eight virion RNA (vRNA) segments, among which the nucleocapsid protein (NP), thought to control whether mRNA or cRNA is produced.The nucleoprotein (NP), which has multiple functions during the virus life cycle, possesses regions that are highly conserved among influenza A, B, and C viruses.It was recently found several NP mutations that affected the efficient incorporation of multiple viral-RNA (vRNA) segments into progeny virions even though a single vRNA segment was incorporated efficiently.This indicates that the respective conserved amino acids in NP may be critical for the assembly and/or incorporation of sets of eight vRNA segments.
Synonyms: Seasonal Influenza A (H1N1) Nucleocapsid Protein, NP, Common flu NP